disable selected options by jQuery

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This will disable/enable the options when you select/remove them, respectively.
$("#theSelect").change(function(){          
    var value = $(this).val();
    if (value === '') return;
    var theDiv = $(".is" + value);

    var option = $("option[value='" + value + "']", this);
    option.attr("disabled","disabled");

    theDiv.slideDown().removeClass("hidden");
    theDiv.find('a').data("option",option);
});


$("div a.remove").click(function () {     
    $(this).parent().slideUp(function() { $(this).addClass("hidden"); });
    $(this).data("option").removeAttr('disabled');
});
Source: 
jQuery - disable selected options

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